Karriere
am Klinikum & Medizinischer Fakultät
PhD (f/m/d) Organoids and Organ-on-Chip
Institute of Neuroanatomy and Developmental Biology, Index Number 6747
Part-time65 %
Limited: 3 years
Start of work:as soon as possible
Application deadline:17.10.2025
The primary objective of this project is to develop an advanced in vitro model of the human retina using Organoid and Organ-on-Chip technologies, with a focus on modeling glaucoma. Throughout the project, the candidate will gain expertise in:
- Cell Culture: Handling and differentiation of human iPSCs and retinal organoids
- Bioengineering: Developing multi-organoid systems, co-culture models, and engineered organoids
- Organ-on-Chip Technology: Designing and implementing microfluidic platforms for retinal modeling
- Immunocytochemistry: Advanced staining and imaging techniques
- Microscopy and Image Analysis: High-resolution imaging and quantitative analysis
- RNA-based Analysis Methods: Including RNA sequencing and single-cell RNA sequencing
- Flow Cytometry / FACS: Cellular analysis and sorting techniques
- Master’s degree in life sciences, molecular biology, or a related field
- Experience in cell culture, particularly with stem cells (e.g., human induced pluripotent stem cells), and proficiency in molecular biology techniques such as qPCR and immunocytochemistry is highly desirable
- Excellent proficiency in English is essential
- Basic programming skills (e.g., R, Python) and familiarity with scientific software (e.g., ImageJ, Prism) are a plus
You are a highly motivated candidate with strong communication skills and a proactive mindset, eager to explore innovative approaches, embrace new challenges and master advanced techniques to achieve project objectives.
Benefits
- A dynamic and highly motivated team in an international work environment
- The opportunity to work with state-of-the-art bioengineering technologies
- The chance to develop cutting-edge skills at the intersection of stem cell biology, bioengineering, and advanced molecular techniques
- Flexible working hours to support work-life balance
The University Hospital of Tübingen is a leading center of German university medicine. Every year, around 75,000 inpatients and around 380,000 outpatients are treated. With over 11,000 employees, it is the largest employer in the region. The quality of patient care is certified with the KTQ seal of approval.
Our vibrant research group is dedicated to developing and utilizing innovative in vitro models derived from human induced pluripotent stem cells (human iPSCs) to investigate developmental processes and disease mechanisms. Our primary focus is on employing retinal organoids and our cutting-edge model system, the retina-on-a-chip, as platforms for disease modeling and drug screening. For more information, please visit our webpage.
Mr. Dr. Kevin Achberger
Index number: 6747
Including CV and cover letter
Application deadline: 17.10.2025
Index number: 6747
Including CV and cover letter
Application deadline: 17.10.2025
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We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States),
severely handicapped persons with equal qualifications are given preferential consideration.
Interview expenses are not covered.
Please note the applicable vaccination regulations.
