The Department I of the University Children’s Hospital Tübingen (Director: Prof. Dr. J. H. Schulte) aims to improve the prognosis of severe diseases in childhood and adolescence through translational research. The research group "Targeted Neuroblastoma Therapy" (PI Prof. J. H. Schulte), in which the advertised position is based, is dedicated to basic, translational, and clinical research into the causes and treatment of neuroblastoma, the most common extracranial tumor in childhood. The group's research areas include novel molecular targeted therapies and targeted immunotherapies, therapy resistance, tumor evolution, and clonal competition. To address these topics, the research group employs high-throughput methods (e.g., Schramm et al., Nature Genetics 2015; Koche et al., Nature Genetics 2020; Fuchs et al., Nature Communications 2023), cell biological techniques (e.g., Berlak et al., Molecular Cancer 2022), single-cell analysis (spatial single-cell RNA sequencing, MACSima, video microscopy), and animal models (e.g., Molenaar et al., Nature Genetics 2012). The research group is integrated into various consortia (e.g., SFB 1588). 

Your tasks:

• Leadership & Team Coordination: Management and supervision of the laboratory research group in close coordination with Prof. Dr. Schulte
• Cutting-Edge Research in "Cell-Fate Decisions": Lead a research project on the cellular decision-making of neuroblastoma cells under ALK inhibition. Depending on your research interests, there is the opportunity to initiate or participate in additional exciting projects in areas such as cellular competition, miRNAs/circRNAs, extrachromosomal DNA (eccDNA), immunotherapies, TCR-transgenic T-cells, or therapy resistance
• Mentorship & Support of Young Scientists: (Co-)supervision of medical and scientific doctoral students.
• Interdisciplinary Collaboration: Close coordination with national and international partners
• Publications & Third-Party Funding Acquisition

We are looking for:

• Dedicated and ambitious personality who is characterized by initiative, team spirit, innovative strength, structured working methods and a high level of motivation and is willing to take on organizational and leadership responsibility
• Completed studies in molecular medicine, biology, biochemistry, chemistry, physics or a comparable subject and a successfully completed doctorate with solid experience in experimental research
• Knowledge of cancer research, immunology and/or molecular biology

Your benefits:

• Working in the diverse environment of a modern university hospital, which, in addition to healthcare, also focuses on medical research and teaching
• Opportunity for Habilitation with long-term scientific career development
• Possibility to establish an independent research group and develop a distinct research profile

We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States), severely handicapped persons with equal qualifications are given preferential consideration. Interview expenses are not covered. Please note the applicable vaccination regulations.