The Core Facility Genomics (head Dr. Nicolas Casadei) was established in 2015 and offers sequencing services for researchers of the University of Tübingen and from overall Germany. Since 2018 it is also one of four DFG NGS (Next Generation Sequencing) competence centers for high throughput sequencing in Germany, the “NGS competence center Tübingen, NCCT”. NGS allows to capture and quantifiy the genome, epigenome, and transcriptome of a biological sample. This is also possible for complex samples that harbor a complex interplay to persist in a specific environment. Besides offering sequencing service, we support research processes in several aspects: by knowledge transfer, by improving reproducibility of research results, and by offering highest reliability. The Core Facility Genomics is part of the Medical Faculty and located at two different sites: at the Institute of Medical Genetics and Applied Genomics and the Institute of Medical Microbiology and Hygiene. 

Your tasks:

• Independent execution and maintenance of bioinformatic pipelines (mainly Nextflow and nf-core) for the analysis of NGS data
• Primary (quality control of sequencing data) and secondary bioinformatics analyses (genome and metagenome assembly and annotation, differential gene expression of bacterial isolates or complex samples)
• Maintenance of IT- and data infrastructure (storage, transfer, digital archiving of NGS data)
• Planning and accurate documentation of analyses, preparation of self-explanatory reports for team members and cooperation partners without informatic background
• Handling of sequencing data of different technologies (Illumina, Nanopore)
• Support our scientific team with the evaluation of sequencing data
• Development of new bioinformatic pipelines and automation of existing processes

Your profile: 

• Motivated team player holding a MSc or PhD degree in bioinformatics or in diverse biological fields with a clear computational focus
• Experience with the application of bioinformatic tools for and processing of NGS data
• Preferably experience with Nextflow or other pipeline management systems
• Computational skills with Unix bash shell script Programming experience with Java, Python, R
• Interest in establishing new tools and pipelines
• Strong communication skills and a good command of the English language, German desirable Additional plus would be experience with system administration

We offer:

• An interesting, versatile and responsible job with the possibility to participate in and contribute to a highly motivated and very skilled team
• A friendly and motivating as well as technically and scientifically competent professional environment in an innovative, rapidly developing field
• A wide range of training and further education opportunities
• Contribution to interesting NGS research projects from a broad microbiological field
• Possibility to extend existing analysis pipelines for microbiological NGS data with room for creativity and own ideas

We offer remuneration in accordance with TV-L (collective wage agreement for the Public Service of the German Federal States), severely handicapped persons with equal qualifications are given preferential consideration. The University of Tübingen strives to hire more female scientific staff, and therefore emphatically requests women to apply for this position. Interview expenses are not covered. Please note the applicable vaccination regulations. Personnel appointments will be made pursuant to the fundamental stipulations of the legal statutes for universities in Germany.